Vishuddha is positioned at the neck region, it is often associated with the thyroid gland in the human endocrine system, wich produces hormones essential for growth and maturation.
Vishuddha is associated with the faculty of higher discrimination, between choosing what is right and wrong, and it is associated with creativity and self-expression. It is known as the 'poison and nectar' centre, closely related to the Bindu chakra, and the secret of immortality is said to reside there. When Vishuddha is closed, we undergo decay and death. When it is open, negative experience is transformed into wisdom and learning.